Multiple Sclerosis Presentation

Job #514

Job Posting Details

Job # 514 Multiple Sclerosis Presentation

Posted Date
Jun 21, 2005 @ 21:11
Respond By
Jun 29, 2005
Word Count
0
Budget
$250
Language
-
Gender
Both
Age Range
-
Category
-

Job Description

This video presentation will be viewed by patients who are considering enrolling in a medical research study for a new multiple sclerosis drug. Computer-animated characters will be used -- we are looking for voiceover talent. Approximately 1100 patients will view the presentation.

We need talent for 9 different languages (native speakers only), including: English, German, French, Czech, Swedish, Polish, Hungarian, Turkish, and Greek.

We are in the process of having the script translated. Prior to recording, voiceover talent should be prepared to review the script for translation errors and also include up to 30 minutes of re-recording time should there be errors in the first recording. Talent must have access to their own recording equipment and be able to post recordings to our FTP site.

The final script will be likely be between 8,000 and 9,000 words. A small portion is listed below.

Multiple sclerosis is an autoimmune disease, meaning your own immune system is damaging your body. In MS, your immune system specifically attacks the myelin that covers the nerves of your brain and spinal cord, or central nervous system. Normally, your immune system helps protect you. It does this by sending in white blood cells and special proteins whenever a foreign substance (like a bacterium or virus) invades your body. But with multiple sclerosis, the immune system mistakenly believes the healthy tissue in your brain and spinal cord are foreign invaders. Immune cells are sent from the blood into the central nervous system, where they produce chemicals that cause inflammation. This inflammation causes the myelin around the nerves to break down, and scar tissue begins to form in its place. This process is called “demyelination.” The name “multiple sclerosis” simply refers to the buildup of scar tissue in the brain and spinal cord. With MS, this scarring, or “sclerosis,” happens in multiple locations inside the central nervous system. As the myelin sheath becomes damaged, the electric signals have a harder time getting though – or become blocked entirely. As the damage progresses, this leads to problems with your muscle control, vision, speech, sensation, and even your thinking. The symptoms of MS and how severe they are vary from person to person. This depends on how much myelin has been lost and what parts of the central nervous system are affected.

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