MEDICAL BIOONCOLOGY Derek

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Elearning
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Description

Educational developments in biooncology

Vocal Characteristics

Language

English

Voice Age

Middle Aged (35-54)

Accents

British (England - South East - Oxford, Sussex) British (General) British (Received Pronunciation - RP, BBC)

Transcript

Note: Transcripts are generated using speech recognition software and may contain errors.
today, Genentech Bio Oncology scientists are focusing on a new monoclonal antibody, her die MEMORISATION inhibitor, to understand its potential significance. Let's review the biology of her receptors. There are four known her receptors. Her one also known a Z G fr her 23 and four. Her activation occurs in a multi step sequence because they heard two. Receptor has no known likened only her 13 and four are activated by like and binding. When Legans bind to the her 13 and four receptors, a change occurs, causing the receptors to assume an open configuration. This prepares them for Di Maria Isation. Her two is unique because it's always in an open configuration, making it the preferred partner of the other herb receptors. Next to her receptors undergo Die memorisation. When open configured receptors pair with one another. This step is crucial in her activation. If her receptors do not dime arise, cell growth, proliferation and survival may not occur. Memorisation then triggers phosphor relation. This activates intracellular, signalling cascades that cause expression of genes that mediates cell growth and survival.